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Biochemistry Insights

Biochemistry Insights

Dirk Geerts Academic Medical Center - University of Amsterdam

eISSN: 11786264 | ISSN: 11786264 | Current volume: 11 | Current issue: 1

Journal Highlights

  • Indexed using ESCI, DOAJ, EBSCO, ProQuest, and PubMed Central (PMC)
  • Published since 2008
  • Publication is subject to payment of an article processing charge (APC)

Biochemistry Insights is an open access, peer reviewed international journal on chemistry, structure and functionality of proteins, carbohydrates, lipids, nucleic acids and smaller molecular components of cells and tissues. Please see the Aims and Scope tab for further information.

This journal is a member of the Committee on Publication Ethics (COPE).

Submission Information

Submit your manuscript here.
Please see the Submission Guidelines tab for more information on how to submit your article to the journal.

Open access article processing charge (APC) information

Publication in the journal is subject to payment of an article processing charge (APC). The APC serves to support the journal and ensures that articles are freely accessible online in perpetuity under a Creative Commons license.

The APC for this journal is currently $1500 USD.
The article processing charge (APC) is payable only if your article is accepted after peer review, before it is published. The APC is subject to taxes where applicable. Tax-exempt status can be indicated by providing appropriate registration numbers when payment is requested. Please see further details here.


Please direct any queries to

Biochemistry Insights is a peer-reviewed, open-access online journal encompassing all topics within the field of biochemistry. This includes the chemistry, structure and function of macromolecules (carbohydrates, lipids, nucleic acids, proteins) and small molecules within cells and tissues. Processes such as the cell cycle, cell signaling, cell metabolism, DNA replication, gene expression, intra- and extracellular cell transport, mRNA processing, and protein synthesis are included but are not exclusive subjects. The journal also accepts articles on related topics applicable to this area, such as techniques, tools, or technology as well as computational modeling that can be applied to the study or utilization of biochemical principles in academia or industry.

Biochemistry Insights welcomes new manuscripts for peer review on the following topics:

  • Chemistry, structure and functionality of proteins, carbohydrates, lipids, nucleic acids and smaller molecular components of cells and tissues
  • Cell metabolism, genomes, protein synthesis, cell signaling, transportation, and signal transduction
  • Technology, outcomes, techniques and applications.

Manuscript Submission

Editor in Chief
Dirk Geerts Academic Medical Center - University of Amsterdam
Supplement Guest Editor - Ligand-Receptor Interactions and Drug Design
Jianrui Song University of Michigan, USA
Yuanyuan Xiao University of Michigan, USA
Xiaojun Zhang University of Southern California, USA
Yanling Zhang Soochow University, China
Editorial Board
Sanjay Adhikari Georgetown University Medical Center, USA
Suleyman Aydin Firat University, Turkey
Andre S. Bachmann College of Human Medicine Michigan State University, USA
Heping Cao United States Department of Agriculture, USA
Katalin Csiszar Cancer Center of Hawaii, University of Hawaii, USA
Omar Deeb Al-Quds Universit, Palestine
Jahan B. Ghasemi University of Tehran, Iran
Hugo Hoenigsberg Instituto de Genetica Evolutiva and Biologia Molecular, Colombia
Gaurav Jain, PhD Chapman University, USA
Caterina A.M. La Porta University of Milan, Italy
Donovan Anthony McGrowder University of the West Indies, Jamaica
Sanjay Mishra IFTM University, Moradabad, UP, India
Amarendra Narayan Misra Central University of Jharkhand, India
Balraj Mittal Sanjay Gandhi Postgraduate Institute of Medical Sciences, India
Mathew Folaranmi Olaniyan College of Natural and Applied Sciences, Achievers University, Nigeria
Annapurna Pamreddy, PhD University of KwaZulu-Natal, South Africa
Mauro Salvi University of Padova, Italy
Fernando Cardona Serrate, PhD Instituto de Biomedicina de Valencia, Spain
Emad Shalaby Cairo University, Egypt
Suren A. Tatulian University of Central Florida, USA
Yong Xue University of California, Los Angeles, USA
Liang-Jun Yan University of North Texas Health Science Center, USA
  • Clarivate Analytics: Emerging Sources Citation Index (ESCI)
  • Directory of Open Access Journals (DOAJ)
  • ProQuest
  • PubMed Central (PMC)
  • This Journal is a member of the Committee on Publication Ethics.

    This Journal recommends that authors follow the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly Work in Medical Journals formulated by the International Committee of Medical Journal Editors (ICMJE).

    Please read the guidelines below then visit the journal’s submission site to upload your manuscript. Please note that manuscripts not conforming to these guidelines may be returned.

    Only manuscripts of sufficient quality that meet the aims and scope of Biochemistry Insights will be reviewed.

    As part of the submission process you will be required to warrant that you are submitting your original work, that you have the rights in the work, that you are submitting the work for first publication in the Journal and that it is not being considered for publication elsewhere and has not already been published elsewhere, and that you have obtained and can supply all necessary permissions for the reproduction of any copyright works not owned by you.

    Please Read the Manuscript Submission Guidelines below before submitting your manuscript here:

    1. Open Access
    2. Article processing charge (APC)
    3. What do we publish?
      3.1 Aims & scope
      3.2 Article types
      3.3 Writing your paper
      3.3.1 Making your article discoverable 
    4. Editorial policies
      4.1 Peer Review Policy
      4.2 Authorship
      4.3 Acknowledgements
      4.4 Funding
      4.5 Declaration of conflicting interests
      4.6 Research ethics and patient consent
      4.7 Clinical Trials
      4.8 Reporting guidelines
    5. Publishing policies
      5.1 Publication ethics
      5.2 Contributor's publishing agreement
    6. Preparing your manuscript
      6.1 Word processing formats
      6.2 Artwork, figures and other graphics
      6.3 Supplementary material
      6.4 Reference style
      6.5 English language editing services
    7. Submitting your manuscript
      7.1 How to submit your manuscript
      7.2 Title, keywords and abstracts
      7.3 Information required for completing your submission
      7.4 ORCID
      7.5 Permissions
    8. On acceptance and publication
      8.1 SAGE Production
      8.2 Continuous publication
      8.3 Promoting your article
    9. Further information

    1. Open Access

    Biochemistry Insights is an open access, peer-reviewed journal. Each article accepted by peer review is
    made freely available online immediately upon publication, is published under a Creative Commons
    license and will be hosted online in perpetuity. Publication costs of the journal are covered by the
    collection of article processing charges which are paid by the funder, institution or author of each
    manuscript upon acceptance. There is no charge for submitting a paper to the journal.

    For general information on open access at SAGE please visit the Open Access page or view our Open
    Access FAQs.

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    2. Article processing charge (APC)

    If, after peer review, your manuscript is accepted for publication, a one-time article processing charge
    (APC) is payable. This APC covers the cost of publication and ensures that your article will be freely
    available online in perpetuity under a Creative Commons license.

    The article processing charge (APC) is $1,500 USD for authors in North America and £1,289 for authors in
    all other countries.*

    *The article processing charge (APC) is payable upon acceptance after peer review and is subject to value
    added tax (VAT) where applicable. If the paying author/institution is based in the European Union, to
    comply with European law, VAT must be added to the APC. Providing a VAT registration number will
    allow an institution to avoid paying this tax, except for UK institutions. Payments can be made in GBP or

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    3. What do we publish?

    3.1 Aims & scope

    Before submitting your manuscript to Biochemistry Insights, please ensure you have read the
    Aims & Scope.

    3.2 Article types

    Biochemistry Insights welcomes submissions of the following types:

    1. Case Report

    • Case reports present interesting or unusual examples of disease, side effects,
      symptoms, treatments, pathogenesis, or unusual circumstances in medicine and
      healthcare. Articles can be accompanied by pictures if necessary—these require
      informed patient consent to publish—and should contribute to the existing
      literature on the condition they report on. Manuscripts must present out of the
      ordinary cases.

    2. Commentaries

    •  Commentaries discuss the findings, implications, and/or outcomes of specific
      research or wider research on a general topic. They elaborate on or offer original
      ideas about a specific paper or a widely-researched subject. Commentaries
      differ from reviews in that they present the author’s original ideas and
      suggestions instead of only collating and reporting the previous research.

    3. Concise reviews

    • These are similar to a review, but less elaborate and often sum up several
      studies in a more concise manner for easier reading and reference.

    4. Editorials

    • Written by the Editor-in-Chief, deputy Editor-in-Chief, Guest Editor or Associate
      Editor of a journal, editorials are intended to inform readers of changes
      concerning the journal, or to introduce supplements, special issues, or new ideas
      relevant to the journal. In limited circumstances individuals other than the
      individuals listed here may propose an editorial topic if they wish.

    5. Expert reviews

    • These are similar to a review but are invited and are generally written by an
      opinion leader in the area.

    6. Images of interest

    • This submission type presents images supporting evaluation of a condition or
      diagnosis of an unusual case. The image may be pathologic or radiographic, and
      must be of high quality and illustrative of the full spectrum of the disorder. Your
      manuscript should contain a summary of the presentation, an indication of the
      features of the image leading to diagnosis or critical to the management of the
      condition. There should also be a discussion of the disease or diagnostic or
      therapeutic process. There may be no more than two figures and the word
      count excluding the abstract and references may be no more than 300 words.

    7. Letters to the Editor

    • Letters to the editor can be submitted on any topic relevant to the journal and
      are usually in response to an article published in the journal. They can suggest
      new subjects to be incorporated by the journal or commend and review papers
      published in the journal. We recommend that individuals considering submitting 
      a letter to the editor should contact the editor in chief first to discuss their
      manuscript. Authors should be aware that letters to the editor are not always
      added to some databases/indexes. Where the editor in chief determines that a
      letter to the editor does not require peer review a 50% discount on the journal’s
      standard applicable article processing fee will apply. Otherwise the standard
      article processing fee will apply, except if the letter addresses an issue on a
      published paper typically addressed through an expression of concern or
      retraction; in such cases no fee will apply.

    8. Meeting reports

    • This manuscript type reports on a meeting with specific relevance to the journal
      it is submitted to. Meetings can be international or national conferences or
      institutional seminars.

    9. Methodologies

    • Methodology manuscripts explain a new methodology or an improvement in
      existing methodologies in therapeutics techniques or medical procedures.

    10. Original research

    • These should detail original experiments/research conducted by the authors.
      Any research on any topic is accepted, provided it falls within the aims and scope
      of the journal. Original research must add to scientific knowledge on the subject
      and must be completed in accordance with ethical principles. Research on
      humans or animals must have applicable ethical approvals.

    11. Perspectives

    • Typically presenting an opinion based on practical experience, these manuscripts
      are similar to opinion articles, but stem from personal experience of the subject
      discussed. They can be written in response to other papers provided the author
      has relevant experience.

    12. Reviews

    • This is a broad-scoped category for short papers discussing a topic relevant to
      the journal. Since these articles are shorter they are often able to be published
      in a timelier manner. They are assigned high processing priority by the

    13. Short commentaries

    • A review is a detailed examination including the benefits and drawbacks of a
      medicine, therapeutic technique, computer program, policy, or anything else
      appropriate to the journal. They are substantially composed of a report on
      previous research. Authors wishing to present original ideas in addition should
      choose the Commentary type. All journals accept unsolicited review
      manuscripts for peer review.

    14. Short reports

    • A short commentary is similar to a commentary but briefer at around 1,000
      words excluding references.

    15. Short reviews

    • Short reports present new research that adds to previous studies. This can be
      reporting on the reliability or unreliability of research or informing readers of
      new factors that may influence the outcome of the study. Authors must
      acknowledge the work they build upon including any unpublished sources.
      Manuscripts should be no longer than approximately 1,000 words excluding

    16. Software or database reviews

    • A short review is similar to a review but briefer at around 1,000 words excluding 

    17. Technical advances

    • A broad-scoped category of manuscript reporting an advance within the journal's
      scope. New procedures, experiments, standard practices, or computational
      methods should be presented in technical advance articles. They report on
      significant advancements in technology that the reader will benefit from learning

    3.3 Writing your paper

    The SAGE Author Gateway has some general advice and on how to get published, plus links to
    further resources.

    3.3.1 Making your article discoverable 

    When writing up your paper, think about how you can make it discoverable. The title,
    keywords and abstract are key to ensuring readers find your article through search
    engines such as Google. For information and guidance on how best to title your article,
    write your abstract and select your keywords, have a look at this page on the Gateway:
    How to Help Readers Find Your Article Online

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    4. Editorial policies

    4.1 Peer review policy

    The journal’s policy is to have manuscripts reviewed by two expert reviewers. Biochemistry
    utilizes a single-blind peer review process in which the reviewer’s name and information
    is withheld from the author. All manuscripts are reviewed as rapidly as possible, while 
    maintaining rigor. Reviewers make comments to the author and recommendations to the
    Editor-in-Chief who then makes the final decision.

    The Editor or members of the Editorial Board may occasionally submit their own manuscripts for
    possible publication in the journal. In these cases, the peer review process will be managed by
    alternative members of the Board and the submitting Editor / Board member will have no
    involvement in the decision-making process.

    Biochemistry Insights is committed to delivering high quality, fast peer-review for your paper,
    and as such has partnered with Publons. Publons is a third party service that seeks to track,
    verify and give credit for peer review. Reviewers for Biochemistry Insights can opt in to Publons
    in order to claim their reviews or have them automatically verified and added to their reviewer
    profile. Reviewers claiming credit for their review will be associated with the relevant journal,
    but the article name, reviewer’s decision and the content of their review is not published on the
    site. For more information visit the Publons website.

    4.2 Authorship

    Papers should only be submitted for consideration once consent is given by all contributing
    authors. Those submitting papers should carefully check that all those whose work contributed
    to the paper are acknowledged as contributing authors.
    The list of authors should include all those who can legitimately claim authorship. This is all
    those who:

    (i) Made a substantial contribution to the concept or design of the work; or acquisition,
    analysis or interpretation of data,
    (ii) Drafted the article or revised it critically for important intellectual content,
    (iii) Approved the version to be published,
    (iv) Each author should have participated sufficiently in the work to take public
    responsibility for appropriate portions of the content.

    Authors should meet the conditions of all of the points above. Each author should have
    participated sufficiently in the work to take public responsibility for appropriate portions of the

    When a large, multicentre group has conducted the work, the group should identify the
    individuals who accept direct responsibility for the manuscript. These individuals should fully
    meet the criteria for authorship.

    Acquisition of funding, collection of data, or general supervision of the research group alone
    does not constitute authorship, although all contributors who do not meet the criteria for
    authorship should be listed in the Acknowledgments section. Please refer to the International
    Committee of Medical Journal Editors (ICMJE) authorship guidelines
    for more information on

    4.3 Acknowledgements

    All contributors who do not meet the criteria for authorship should be listed in an
    Acknowledgements section. Examples of those who might be acknowledged include a person
    who provided purely technical help, or a department chair who provided only general support.

    4.3.1 Writing assistance

    Individuals who provided writing assistance, e.g. from a specialist communications company, do
    not qualify as authors and so should be included in the Acknowledgements section. Authors
    must disclose any writing assistance – including the individual’s name, company and level of
    input – and identify the entity that paid for this assistance.

    It is not necessary to disclose use of language polishing services.

    Any acknowledgements should appear first at the end of your article prior to your Declaration of
    Conflicting Interests (if applicable), any notes and your References.

    4.4 Funding

    Biochemistry Insights requires all authors to acknowledge their funding in a consistent fashion
    under a separate heading. Please visit the Funding Acknowledgements page on the SAGE
    Journal Author Gateway to confirm the format of the acknowledgment text in the event of
    funding, or state that: This research received no specific grant from any funding agency in the
    public, commercial, or not-for-profit sectors.

    4.5 Declaration of conflicting interests

    It is the policy of Biochemistry Insights to require a declaration of conflicting interests from all
    authors enabling a statement to be carried within the paginated pages of all published articles.

    Please ensure that a ‘Declaration of Conflicting Interests’ statement is included at the end of
    your manuscript, after any acknowledgements and prior to the references. If no conflict exists,
    please state that ‘The Author(s) declare(s) that there is no conflict of interest’.

    For guidance on conflict of interest statements, please see the ICMJE recommendations.

    4.6 Research ethics and patient consent

    Medical research involving human subjects must be conducted according to the World Medical
    Association Declaration of Helsinki.

    Submitted manuscripts should conform to the ICMJE Recommendations for the Conduct,
    Reporting, Editing, and Publication of Scholarly Work in Medical Journals
    , and all papers
    reporting animal and/or human studies must state in the methods section that the relevant
    Ethics Committee or Institutional Review Board provided (or waived) approval. Please ensure
    that you have provided the full name and institution of the review committee, in addition to the
    approval number.

    For research articles, authors are also required to state in the methods section whether
    participants provided informed consent and whether the consent was written or verbal.
    Information on informed consent to report individual cases or case series should be included in
    the manuscript text. A statement is required regarding whether written informed consent for
    patient information and images to be published was provided by the patient(s) or a legally
    authorized representative.

    Please also refer to the ICMJE Recommendations for the Protection of Research Participants

    All research involving animals submitted for publication must be approved by an ethics
    committee with oversight of the facility in which the studies were conducted. The journal has
    adopted the Consensus Author Guidelines on Animal Ethics and Welfare for Veterinary Journals
    published by the International Association of Veterinary Editors.

    4.7 Clinical trials

    Biochemistry Insights conforms to the ICMJE requirement that clinical trials are registered in a
    WHO-approved public trials registry at or before the time of first patient enrolment as a
    condition of consideration for publication. The trial registry name and URL, and registration
    number must be included at the end of the abstract.

    4.8 Reporting guidelines

    The relevant EQUATOR Network reporting guidelines should be followed depending on the type
    of study. For example, all randomized controlled trials submitted for publication should include
    a completed CONSORT flow chart as a cited figure and the completed CONSORT checklist should
    be uploaded with your submission as a supplementary file. Systematic reviews and metaanalyses
    should include the completed PRISMA flow chart as a cited figure and the completed
    PRISMA checklist should be uploaded with your submission as a supplementary file. The
    EQUATOR wizard can help you identify the appropriate guideline.

    Other resources can be found at NLM’s Research Reporting Guidelines and Initiatives.

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    5. Publishing policies

    5.1 Publication ethics

    SAGE is committed to upholding the integrity of the academic record. We encourage authors to
    refer to the Committee on Publication Ethics’ International Standards for Authors and view the
    Publication Ethics page on the SAGE Author Gateway.

    5.1.1 Plagiarism

    Biochemistry Insights and SAGE take issues of copyright infringement, plagiarism or other
    breaches of best practice in publication very seriously. We seek to protect the rights of our
    authors and we always investigate claims of plagiarism or misuse of published articles. Equally, 
    we seek to protect the reputation of the journal against malpractice. Submitted articles may be
    checked with duplication-checking software. Where an article, for example, is found to have
    plagiarized other work or included third-party copyright material without permission or with
    insufficient acknowledgement, or where the authorship of the article is contested, we reserve
    the right to take action including, but not limited to: publishing an erratum or corrigendum
    (correction); retracting the article; taking up the matter with the head of department or dean of
    the author's institution and/or relevant academic bodies or societies; or taking appropriate legal

    5.1.2 Prior publication

    If material has been previously published, it is not generally acceptable for publication in a SAGE
    journal. However, there are certain circumstances where previously published material can be
    considered for publication. Please refer to the guidance on the SAGE Author Gateway or if in
    doubt, contact the Editor at the address given below.

    5.2 Contributor's publishing agreement

    Before publication SAGE requires the author as the rights holder to sign a Journal Contributor’s
    Publishing Agreement. Biochemistry Insights publishes manuscripts under Creative Commons
    . The standard license for the journal is Creative Commons by Attribution NonCommercial
    (CC BY-NC), which allows others to re-use the work without permission as long as
    the work is properly referenced and the use is non-commercial. For more information, you are
    advised to visit SAGE's OA licenses page.

    Alternative license arrangements are available, for example, to meet particular funder
    mandates, made at the author’s request.

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    6. Preparing your manuscript

    6.1 Word processing formats

    The preferred format for your manuscript is Word. LaTeX files are also accepted. Word and
    (La)Tex templates are available on the Manuscript Submission Guidelines page of our Author

    6.2 Artwork, figures and other graphics

    For guidance on the preparation of illustrations, pictures and graphs in electronic format, please
    visit SAGE’s Manuscript Submission Guidelines

    Figures supplied in color will appear in color online.

    6.3 Supplementary material

    This journal is able to host additional materials online (e.g. datasets, podcasts, videos, images
    etc) alongside the full-text of the article. These will be subjected to peer-review alongside the
    article. For more information please refer to our guidelines on submitting supplementary files,
    which can be found within our Manuscript Submission Guidelines page.

    6.4 Reference style

    Biochemistry Insights adheres to the AMA reference style. Please review the guidelines on AMA
    to ensure your manuscript conforms to this reference style.

    If you use EndNote to manage references, you can download the AMA output file here.

    6.5 English language editing services

    Authors seeking assistance with English language editing, translation, or figure and manuscript
    formatting to fit the journal’s specifications should consider using SAGE Language Services. Visit
    SAGE Language Services on our Journal Author Gateway for further information. 

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    7. Submitting your manuscript

    7.1 How to submit your manuscript

    To submit your manuscript to Biochemistry Insights, please visit our manuscript submission
    . Please be sure to ensure that references are formatted with AMA reference style.

    7.2 Title, keywords and abstracts

    Please supply a title, short title, an abstract and keywords to accompany your article. The title,
    keywords and abstract are key to ensuring readers find your article online through online search
    engines such as Google. Please refer to the information and guidance on how best to title your
    article, write your abstract and select your keywords by visiting the SAGE Journal Author
    Gateway for guidelines on How to Help Readers Find Your Article Online. 

    7.3 Information required for completing your submission

    Provide full contact details for the corresponding author including email, mailing address and
    telephone numbers. Academic affiliations are required for all co-authors. These details should
    be presented separately to the main text of the article to facilitate anonymous peer review.

    You will be asked to provide contact details and academic affiliations for all co-authors via the
    submission system and identify who is to be the corresponding author. These details must
    match what appears on your manuscript. At this stage please ensure you have included all the 
    required statements and declarations and uploaded any additional supplementary files
    (including reporting guidelines where relevant).

    7.4 ORCID

    As part of our commitment to ensuring an ethical, transparent and fair peer review process
    SAGE is a supporting member of ORCID, the Open Researcher and Contributor ID. ORCID
    provides a persistent digital identifier that distinguishes researchers from every other researcher
    and, through integration in key research workflows such as manuscript and grant submission,
    supports automated linkages between researchers and their professional activities ensuring that
    their work is recognized.

    We encourage all authors to add their ORCIDs to their SAGE Track accounts and include their
    ORCIDs as part of the submission process. If you don’t already have one you can create one

    7.5 Permissions

    Authors are responsible for obtaining permission from copyright holders for reproducing any
    illustrations, tables, figures or lengthy quotations previously published elsewhere. For further
    information including guidance on fair dealing for criticism and review, please visit our
    Frequently Asked Questions on the SAGE Journal Author Gateway.

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    8. On acceptance and publication

    If your paper is accepted for publication after peer review, you will first be asked to complete the
    contributor’s publishing agreement. Once your manuscript files have been checked for SAGE Production,
    the corresponding author will be asked to pay the article processing charge (APC) via a payment link.
    Once the APC has been processed, your article will be prepared for publication and can appear online
    within an average of 30 days. Please note that no production work will occur on your paper until the
    APC has been received.

    8.1 SAGE Production

    Your SAGE Production Editor will keep you informed as to your article’s progress throughout the
    production process. Proofs will be sent by PDF to the corresponding author and should be
    returned promptly. Authors are reminded to check their proofs carefully to confirm that all
    author information, including names, affiliations, sequence and contact details are correct, and
    that Funding and Conflict of Interest statements, if any, are accurate. Please note that if there
    are any changes to the author list at this stage all authors will be required to complete and sign
    a form authorizing the change.

    8.2 Online publication

    One of the many benefits of publishing your research in an open access journal is the speed to
    publication. With no page count constraints, your article will be published online in a fully
    citable form with a DOI number as soon as it has completed the production process. At this time
    it will be completely free to view and download for all. 

    8.3 Promoting your article

    Publication is not the end of the process! You can help disseminate your paper and ensure it is
    as widely read and cited as possible. The SAGE Author Gateway has numerous resources to help
    you promote your work. Visit the Promote Your Article page on the Gateway for tips and advice.
    In addition, SAGE is partnered with Kudos, a free service that allows authors to explain, enrich,
    share, and measure the impact of their article. Find out how to maximize your article’s impact
    with Kudos. 

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    9. Further information

    Any correspondence, queries or additional requests for information on the Manuscript Submission
    process should be sent to the Biochemistry Insights editorial office as follows:

    Kiley Allen

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