Innate Immunity

Innate Immunity

2016 Impact Factor: 2.342
2016 Ranking: 179/286 in Biochemistry & Molecular Biology | 104/150 in Immunology | 72/128 in Medicine, Research & Experimental | 66/124 in Microbiology
Source: 2016 Journal Citation Reports® (Clarivate Analytics, 2017); Indexed in PubMed: MEDLINE
Formerly the Journal of Endotoxin Research

Otto Holst Research Center Borstel, Germany
Assistant Editor
Patricia M. Sanchez Carballo Research Center Borstel, Germany
Reviews Editor
Alan S. Cross University of Maryland, USA

Other Titles in:
Biophysics | Cell Biology | Immunology

eISSN: 17534267 | ISSN: 17534259 | Current volume: 23 | Current issue: 4 Frequency: 8 Times/Year

Innate Immunity is a highly ranked, peer reviewed scholarly journal, first published as Journal of Endotoxin Research (JER) in 1994 as the official journal of the International Endotoxin Society (IES). Over 10 years of being known as the IES, the society recognised a significant increase in research in innate immunity not related to endotoxins. In response to this the society became the International Endotoxin and Innate Immunity Society (IEIIS) in 2005.

The journal’s coverage has changed in line with the society, and it increasingly publishes articles dealing with innate immunity research not related to endotoxins. A joint decision was made between the publisher and the IEIIS to re-launch the journal in 2008 with the new name Innate Immunity, to reflect the broader range of coverage of the society and in the journal.

An publication charge of $250/£155 is required for publication. It is payable upon acceptance and subject to VAT* where applicable.

*If the paying author/institution is based in the European Union, to comply with European law, Value Added Tax must be added to the publication charge. Providing a VAT registration number will allow an institution to avoid paying this tax, except for UK institutions. An invoice will be issued in GBP.

This journal is a member of the Committee on Publication Ethics (COPE)

Innate Immunity is a highly ranked, peer-reviewed scholarly journal and is the official journal of the International Endotoxin & Innate Immunity Society (IEIIS). The journal welcomes manuscripts from researchers actively working on all aspects of innate immunity including biologically active bacterial, viral, fungal, parasitic, and plant components, as well as relevant cells, their receptors, signaling pathways, and induced mediators.

The aim of the Journal is to provide a single, interdisciplinary forum for the dissemination of new information on innate immunity in humans, animals, and plants to researchers. The Journal creates a vehicle for the publication of articles encompassing all areas of research, basic, applied, and clinical. The subject areas of interest include, but are not limited to, research in biochemistry, biophysics, cell biology, chemistry, clinical medicine, immunology, infectious disease, microbiology, molecular biology, and pharmacology.

The Journal includes original research articles, notes, and (mini)reviews. It is the intention that each issue of the Journal also will contain an invited review of a scientific topic of current interest. If you have any questions relating to the appropriateness of your manuscript for submission to Innate Immunity, please contact the Editor-in-Chief, Dr. Otto Holst at

An publication charge of $250/£155 is required for publication. It is payable upon acceptance and subject to VAT* where applicable.

*If the paying author/institution is based in the European Union, to comply with European law, Value Added Tax must be added to the publication charge. Providing a VAT registration number will allow an institution to avoid paying this tax, except for UK institutions. An invoice will be issued in GBP.

Editorial Advisory Board
Sven Brandau University Hospital Essen, Germany
Albrecht Bufe Bochum, Germany
Jean-Marc Cavaillon Paris, France
Dipshikha Chakravortty Bangalore, India
Pedro Esteves Universidade do Porto, Portugal
Eugen Faist München, Germany
Koichi Fukase Osaka University, Japan
Andrew Gewirtz Georgia State University, USA
Amy Hise Case Western Reserve University, USA
Johannes Hübner München, Germany
Simon Jackson Plymouth, UK
Roman Jerala Kemijski Institut - KI, Slovenia
Carsten Kirschning Essen, Germany
Paul Kosma Wien, Austria
Martin Krönke Köln, Germany
Coen Kuijl  
Shoichi Kusumoto Osaka, Japan
Simon MacKenzie Stirling, UK
Andrei E Medvedev Farmington, USA
Kensuke Miyake Tokyo, Japan
Antonio Molinaro Napoli, Italy
Sven Müller-Loennies Borstel, Germany
Robert S Munford Bethesda, USA
Mari-Anne Newman Copenhagen, Denmark
Nades Palaniyar Toronto, Canada
Francesco Peri University of Milano-Bicocca, Italy
Dana Philpott Toronto, Canada
Gerald B Pier Boston, USA
Pirkko Pussinen Helsinki, Finland
Mikael Skurnik Helsinki, Finland
M Stephen Trent Austin, USA
Klaus Überla Universitätsklinikum Erlangen, Germany
Stefanie Vogel Bethesda, USA
Mamoru Watanabe Tokyo, Japan
Dirk Werling The Royal Veterinary College, UK
Chris Whitfield Guelph, Canada
Takashi Yokochi Aichi, Japan
Holm Zerbe München, Germany
  • EMBASE/Excerpta Medica
  • EMCare
  • SciVal
  • Scopus
  • This Journal is a member of the Committee on Publication Ethics. This Journal recommends that authors follow the Uniform Requirements for Manuscripts Submitted to Biomedical Journals formulated by the International Committee of Medical Journal Editors (ICMJE).

    Please read the guidelines below then visit the Journal’s submission site to upload your manuscript. Please note that manuscripts not conforming to these guidelines may be returned.

    Each submitted manuscript must contain original research that has not been published previously or is not considered for publication in other media. Manuscripts must be written in English. Authors are requested to supply the Editor-in-Chief and all reviewers with electronic versions of other papers cited that are under review or in press elsewhere.

    As part of the submission process you will be required to warrant that you are submitting your original work, that you have the rights in the work, that you are submitting the work for first publication in the Journal and that it is not being considered for publication elsewhere and has not already been published elsewhere, and that you have obtained and can supply all necessary permissions for the reproduction of any copyright works not owned by you.

    1. Article types
    2. Editorial Policies
      2.1 Peer review policy
      2.2 Authorship
      2.3 Acknowledgments
      2.4 Funding
      2.5 Declaration of conflicting interests
      2.6 Research ethics and patient consent
      2.7 Clinical Trials
      2.8 Reporting Guidelines
    3. Publishing Policies
      3.1 Publication Ethics
      3.2 Contributor's publishing agreement
      3.3 Open Access and author archiving
      3.4 Permissions
      3.5 Publication charges
    4. Preparing your manuscript
      4.1 Formatting your manuscript
      4.2 Word processing formats
      4.3 Artwork, figures and other graphics
      4.4 Supplementary material
      4.5 Journal layout
      4.6 Standard abbreviations
      4.7 English language editing services
    5. Submitting your manuscript
    6. On acceptance and publication
      6.1 SAGE Production
      6.2 Access to your published article
      6.3 Online First publication
    7. Further Information

    Back to top

    1. Article types

    Innate Immunity is a highly ranked, peer reviewed scholarly journal which publishes (invited) Reviews and Original Articles. At present there are no length restrictions for manuscripts, however authors should write papers that are as concise as possible. Too verbose or redundant Introduction and/or Discussion sections should be avoided.

    Back to top

    2. Editorial policies

    2.1 Peer review policy

    Only manuscripts of sufficient quality that meet the aims and scope of Innate Immunity will be reviewed.

    Innate Immunity operates a conventional single-blind reviewing policy in which the reviewer’s name is always concealed from the submitting author. All manuscripts are reviewed initially by the Editor and only those papers that meet the scientific and editorial standards of the journal, and fit within its aims and scopes, will be sent for outside review. Of these manuscripts, each is reviewed by at least two referees, one of which will be an Editorial Advisory Board member. All manuscripts are reviewed as rapidly as possible, and an editorial decision is generally reached within 4-6 weeks of submission.

    As part of the submission process you will be asked to provide the names of three peers who could be called upon to review your manuscript. Recommended reviewers should be experts in their fields and should be able to provide an objective assessment of the manuscript. Please be aware of any conflicts of interest when recommending reviewers. Examples of conflicts of interest include (but are not limited to) the below:  

    • The reviewer should have no prior knowledge of your submission
    • The reviewer should not have recently collaborated with any of the authors
    • Reviewer nominees from the same institution as any of the authors are not permitted

    Authors may also indicate referees who they would prefer not review their work.

    Please note that the Editor is not obliged to invite any recommended reviewers to assess your manuscript.

    2.2 Authorship

    Papers should only be submitted for consideration once consent is given by all contributing authors. Those submitting papers should carefully check that all those whose work contributed to the paper are acknowledged as contributing authors.

    The list of authors should include all those who can legitimately claim authorship. This is all those who:

    • Made a substantial contribution to the concept and design, acquisition of data or analysis and interpretation of data,
    • Drafted the article or revised it critically for important intellectual content,
    • Approved the version to be published.

    Authors should meet the conditions of all of the points above. Each author should have participated sufficiently in the work to take public responsibility for appropriate portions of the content. When a large, multicentre group has conducted the work, the group should identify the individuals who accept direct responsibility for the manuscript. These individuals should fully meet the criteria for authorship.

    Acquisition of funding, collection of data, or general supervision of the research group alone does not constitute authorship, although all contributors who do not meet the criteria for authorship should be listed in the Acknowledgments section. Please refer to the International Committee of Medical Journal Editors (ICMJE) authorship guidelines for more information on authorship.

    2.3 Acknowledgements

    All contributors who do not meet the criteria for authorship should be listed in an Acknowledgements section. Examples of those who might be acknowledged include a person who provided purely technical help, or a department chair who provided only general support.

    2.3.1 Writing Assistance

    Individuals who provided writing assistance, e.g. from a specialist communications company, do not qualify as authors and so should be included in the Acknowledgements section. Authors must disclose any writing assistance – including the individual’s name, company and level of input – and identify the entity that paid for this assistance”). It is not necessary to disclose use of language polishing services.

    2.4 Funding

    Innate Immunity requires all authors to acknowledge their funding in a consistent fashion under a separate heading.  Please visit the Funding Acknowledgements page on the SAGE Journal Author Gateway to confirm the format of the acknowledgment text in the event of funding, or state that: This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.

    2.5 Declaration of conflicting interests

    It is the policy of Innate Immunity to require a declaration of conflicting interests from all authors enabling a statement to be carried within the paginated pages of all published articles.
    Please ensure that a ‘Declaration of Conflicting Interests’ statement is included at the end of your manuscript, after any acknowledgements and prior to the references. If no conflict exists, please state that ‘The Author(s) declare(s) that there is no conflict of interest’.

    For guidance on conflict of interest statements, please see the ICMJE recommendations here

    2.6 Research ethics and patient consent

    Medical research involving human subjects must be conducted according to the World Medical Association Declaration of Helsinki

    Submitted manuscripts should conform to the ICMJE Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly Work in Medical Journals, and all papers reporting animal and/or human studies must state in the methods section that the relevant Ethics Committee or Institutional Review Board provided (or waived) approval. Please ensure that you have provided the full name and institution of the review committee, in addition to the approval number.

    For research articles, authors are also required to state in the methods section whether participants provided informed consent and whether the consent was written or verbal.

    Information on informed consent to report individual cases or case series should be included in the manuscript text. A statement is required regarding whether written informed consent for patient information and images to be published was provided by the patient(s) or a legally authorized representative.

    Please also refer to the ICMJE Recommendations for the Protection of Research Participants

    All research involving animals that is submitted for publication must be approved by an ethics committee with oversight of the facility in which the studies were conducted. The journal has adopted the Consensus Author Guidelines on Animal Ethics and Welfare for Veterinary Journals published by the International Association of Veterinary Editors.

    2.7 Clinical trials

    Innate Immunity conforms to the ICMJE requirement that clinical trials are registered in a WHO-approved public trials registry at or before the time of first patient enrolment as a condition of consideration for publication. The trial registry name and URL, and registration number must be included at the end of the abstract.

    2.8 Reporting guidelines

    The relevant EQUATOR Network reporting guidelines should be followed depending on the type of study. For example, all randomized controlled trials submitted for publication should include a completed Consolidated Standards of Reporting Trials (CONSORT) flow chart as a cited figure, and a completed CONSORT checklist as a supplementary file.

    Other resources can be found at NLM’s Research Reporting Guidelines and Initiatives

    Back to top

    3. Publishing policies

    3.1 Publication ethics

    SAGE is committed to upholding the integrity of the academic record. We encourage authors to refer to the Committee on Publication Ethics’ International Standards for Authors and view the Publication Ethics page on the SAGE Author Gateway

    3.1.1 Plagiarism

    Innate Immunity and SAGE take issues of copyright infringement, plagiarism or other breaches of best practice in publication very seriously. We seek to protect the rights of our authors and we always investigate claims of plagiarism or misuse of published articles. Equally, we seek to protect the reputation of the journal against malpractice. Submitted articles may be checked with duplication-checking software. Where an article, for example, is found to have plagiarised other work or included third-party copyright material without permission or with insufficient acknowledgement, or where the authorship of the article is contested, we reserve the right to take action including, but not limited to: publishing an erratum or corrigendum (correction); retracting the article; taking up the matter with the head of department or dean of the author's institution and/or relevant academic bodies or societies; or taking appropriate legal action.

    3.2 Contributor's publishing agreement

    Before publication, SAGE requires the author as the rights holder to sign a Journal Contributor’s Publishing Agreement. SAGE’s Journal Contributor’s Publishing Agreement is an exclusive licence agreement which means that the author retains copyright in the work but grants SAGE the sole and exclusive right and licence to publish for the full legal term of copyright. Exceptions may exist where an assignment of copyright is required or preferred by a proprietor other than SAGE. In this case copyright in the work will be assigned from the author to the society. For more information please visit our Frequently Asked Questions on the SAGE Journal Author Gateway.

    3.3 Open Access and author archiving

    Innate Immunity offers optional open access publishing via the SAGE Choice programme. For more information please visit the SAGE Choice website. For information on funding body compliance, and depositing your article in repositories, please visit SAGE Publishing Policies on our Journal Author Gateway.

    3.4 Permissions

    Authors are responsible for obtaining permission from copyright holders for reproducing any illustrations, tables, figures or lengthy quotations previously published elsewhere. For further information including guidance on fair dealing for criticism and review, please visit our Frequently Asked Questions on the SAGE Journal Author Gateway

    3.5 Publication charges

    A publication charge of $250/£155 is required for publication. It is payable upon acceptance and subject to VAT* where applicable.

    *If the paying author/institution is based in the European Union, to comply with European law, Value Added Tax must be added to the publication charge. Providing a VAT registration number will allow an institution to avoid paying this tax, except for UK institutions. An invoice will be issued in GBP.

    Back to top

    4. Preparing your manuscript

       4.1 Formatting your manuscript

    Papers should be set out as follows, with each section beginning on a separate sheet: title page, summary, text, acknowledgements, references, tables, captions to illustrations.

    Title page: The title page should give the following information: (1) title of the article (in bold), as short and informative as possible, without any abbreviation; (2) one first name, initials (if applicable) and last name of each author; (3) address of the department or institution to which the work should be attributed; (4) name, telephone, fax number and email address of the author responsible for correspondence and to whom the proof, invoices for coloured figures (if applicable) and the publication charge, and e-prints should be sent.

    Abstract: This should consist of no more than 200 words summarizing the contents of the article. Please do not subdivide, e.g. Background, Aim, Results, Conclusion, or similar. It is important, especially for indexing services, that the abstract should be intelligible without reference to the full text or to literature references. The abstract must stand alone, and it should be presumed that the reader has some knowledge of the subject but has not read the paper. Except in the case of a standard abbreviation (see 6.), do not abbreviate a term when used only once. When used more than once, do abbreviate and define.

    Keywords: Authors are requested to supply three to five keywords (words or phrases) in alphabetical order.

    The title, keywords and abstract are key to ensuring readers find your article online through online search engines such as Google. Please refer to the information and guidance on how best to title your article, write your abstract and select your keywords by visiting the SAGE Journal Author Gateway for guidelines on How to Help Readers Find Your Article Online

    Text: Headings should be appropriate to the nature of the paper. In general, those for experimental papers should follow the usual conventions. Reviews can be subdivided as the author desires; the use of headings enhances readability.

    The sugar absolute configuration symbols L and D are written as small capitals. The configuration symbols (R) and (S) are written in brackets and italicized. The g for g force is italicized. Otherwise, authors should apply the rules and recommendations of IUBMB and IUPAC, i.e. for abbreviation of chemical names, nomenclature of chemical compounds and enzymes, etc. With regard to the nomenclature of carbohydrates, authors are asked to follow recommendations published in Carbohydr Res 1997; 297: 1-92. The use of LIPID MAPS Initiative (Fahy E, et al., J Lipid Res 2005; 46: 839-862) is strongly recommended for the use of lipid classification, nomenclature and structural representation.

    Proprietary names: Proprietary names of drugs, instruments etc. should be indicated by the use of initial capital letters.

    Abbreviations and units: All measurements should be expressed in metric units. For more detailed recommendations, authors may consult the Royal Society of Medicine publication entitled Units, Symbols and Abbreviations: A Guide for Biological and Medical Editors and Authors or USA equivalent.

    References: The accuracy of references is the responsibility of the author. Innate Immunity adheres to the SAGE Vancouver reference style. Review the guidelines on SAGE Vancouver to ensure your manuscript conforms to this reference style.

    If you use EndNote to manage references, you can download the SAGE Vancouver output file here

    4.2 Word processing formats

    Preferred formats for the text and tables of your manuscript are Word DOC, RTF, XLS. LaTeX files are also accepted. The text should be 1.5 spaced throughout and with a minimum of 3cm for left and right hand margins and 5cm at head and foot. Text should be standard 10 or 12 point. Word and (La)Tex templates are available on the Manuscript Submission Guidelines page of our Author Gateway.

    4.3 Artwork, figures and other graphics

    For guidance on the preparation of illustrations, pictures and graphs in electronic format, please visit SAGE’s Manuscript Submission Guidelines  

    Figures supplied in colour will appear in colour online regardless of whether or not these illustrations are reproduced in colour in the printed version. For specifically requested colour reproduction in print, you will receive information regarding the costs from SAGE after receipt of your accepted article.

    4.4 Supplementary material

    This journal is able to host additional materials online (e.g. datasets, podcasts, videos, images etc) alongside the full-text of the article. These will be subjected to peer-review alongside the article.  For more information please refer to our guidelines on submitting supplementary files, which can be found within our Manuscript Submission Guidelines page.

    4.5 Journal layout

    Innate Immunity conforms to the SAGE house style, please review the guidelines onSAGE house style.

    4.6 Standard abbreviations
    Standard Abbreviations and symbols should be used as listed in this document. The abbreviation should be defined in full in the first instance used, unless they are standard units of measurement. Avoid any use of abbreviations in the article title and abstract.

    4.7 English language editing services

    Authors seeking assistance with English language editing, translation, or figure and manuscript formatting to fit the journal’s specifications should consider using SAGE Language Services. Visit SAGE Language Services on our Journal Author Gateway for further information.

    Back to top

    5. Submitting your manuscript

    5.1 How to submit your manuscript

    Innate Immunity is hosted on SAGE Track, a web based online submission and peer review system powered by ScholarOne™ Manuscripts. Visit to login and submit your article online.

    IMPORTANT: Please check whether you already have an account in the system before trying to create a new one. If you have reviewed or authored for the journal in the past year it is likely that you will have had an account created.  For further guidance on submitting your manuscript online please visit ScholarOne Online Help.

    Back to top

    6. On acceptance and publication

    6.1 SAGE Production

    Your SAGE Production Editor will keep you informed as to your article’s progress throughout the production process. Proofs will be sent by PDF to the corresponding author and should be returned promptly.

    6.2 Access to your published article

    SAGE provides authors with online access to their final article.

    6.3 Online First publication

    Online First allows final revision articles (completed articles in queue for assignment to an upcoming issue) to be published online prior to their inclusion in a final journal issue which significantly reduces the lead time between submission and publication. For more information please visit our Online First Fact Sheet 

    Back to top

    7. Further Information

    Any correspondence, queries or additional requests for information on the manuscript submission process should be sent to the Editor-in-Chief as follows:

    Dr Otto Holst
    Associate Professor
    Division of Structural Biochemistry
    Research Center Borstel
    Parkallee 4a
    D-23845 Borstel

    Back to top

    Individual Subscription, Combined (Print & E-access)

    Institutional Subscription, E-access

    Institutional Backfile Purchase, E-access (Content through 1998)

    Institutional Subscription, Print Only

    Institutional Subscription, Combined (Print & E-access)

    Institutional Subscription & Backfile Lease, E-access Plus Backfile (All Online Content)

    Institutional Subscription & Backfile Lease, Combined Plus Backfile (Current Volume Print & All Online Content)

    Individual, Single Print Issue

    Institutional, Single Print Issue